Meanwhile, that big picture just keeps getting more interesting. Vitamin D now looks like the tip of the solar iceberg. Sunlight triggers the release of a number of other important compounds in the body, not only nitric oxide but also serotonin and endorphins. It reduces the risk of prostate, breast, colorectal, and pancreatic cancers. It … Continue reading Is sunscreen the new margarine?
Senescent cells are classified as cells that are not older and deteriorated but also compromise the function of cells around them. Studies in animals have shown that the removal of these particular cells can improve some of the effects of aging; including delaying the onset of cataracts.
Wall Street Journal
The effect of isolation is extraordinarily powerful,” says Donald Berwick, former administrator of the Centers for Medicare and Medicaid Services. “If we want to achieve health for our population, especially vulnerable people, we have to address loneliness.” The Trump administration is looking at expanding faith-based partnerships to combat isolation among seniors, says U.S. Assistant Secretary … Continue reading The loneliest generation: americans, more than ever, are aging alone
But perhaps the most well-studied part of anti-aging is the role of telomeres, the protective caps at the ends of chromosomes that naturally get shorter as we get older. As we age, telomeres shorten naturally, but there are some things we can do to slow, or even, in small part, reverse that process. Endurance exercises reversed the shortening of … Continue reading DNA researchers pinpoint the type of exercise that could extend life
Relationships deeply affect people’s physical and mental health—including relationships with younger generations. George Vaillant, the psychiatrist who led the study for decades, found that those in middle age or older who invest in nurturing the next generation were three times as likely to be happy as those who fail to do so. “Biology flows downhill,” he … Continue reading The real trick to staying young forever
Horvath’s clock proved a very clear relationship between this methylation?—?both gained and lost?—?and the chronological age of humans, or as Horvath puts it, “the number on your passport.” He also believes it bears some relationship to biological age, the very definition of which is so hotly debated among biologists that Horvath compares its vagueness to … Continue reading Is Horvath’s Clock the Smoking Gun of Biological Aging?
Barzilai’s big plan isn’t necessarily less quixotic than those being dreamed up at Silicon Valley biotechs. It’s just quixotic in a completely different way. Rather than trying to develop a wildly expensive, highly speculative therapy that will likely only benefit the billionaire-demigod set, Barzilai wants to convince the FDA to put its seal of approval on … Continue reading Forget the blood of teens. This pill promises to extend life for a nickel a pop
A critical aspect of fasting — which is different from simply restricting calories — is that the body undergoes a metabolic switch from using glucose to using ketones as fuel, a result of the depletion of liver energy stores and the mobilization of fat. The presence of ketones in the blood signifies that on the … Continue reading Is fasting the fountain of youth?
Senescent cells were first described in the late 1950s but remained largely a curiosity until 2008 when their dark nature was revealed by Judith Campisi and others. She found that the cells secrete a cocktail of foul factors, which poison the surrounding tissue. Niedernhofer likens them to that bad strawberry in the punnet, rotting everything … Continue reading Want to live forever? Flush out your zombie cells
The amount of data you slough off everyday—in lab tests, medical images, genetic profiles, liquid biopsies, electrocardiograms, to name just a few—is overwhelming by itself. Throw in the stuff from medical claims, clinical trials, prescriptions, academic research, and more, and the yield is something on the order of 750 quadrillion bytes every day—or some 30% … Continue reading Tech’s next big wave: big data meets biology
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